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Items for "rat"
Direct thrombin inhibitors built on the azaphenylalanine scaffold provoke degranulation of mast cells
The main structural feature of direct thrombin inhibitor LK-732 responsible for the appropriate interaction at the thrombin active site is a strong basic group...
Keywords: Thrombin inhibitors, azaphenylalanine scaffold, mast cell degranulation, basicity, rat
00/0000 | Thrombosis and Haemostasis, SchattauerRat models of myocardial infarction. Pathogenetic insights and clinical relevance
Animal models of cardiovascular pathology contribute towards understanding and treatment of a broad range of conditions...
Keywords: rat, Animal model, myocardial infarction, microvasculature
11/2006 | Thrombosis and Haemostasis, SchattauerGenetic strain differences in platelet aggregation and thrombus formation of laboratory rats
Rats are employed to investigate the role of platelets in thrombus formation under flow conditions in vivo and to evaluate the pre-clinical potential of antiplatelet drugs...
Keywords: platelet aggregation, rat, strain difference, thrombus formation
04/2007 | Thrombosis and Haemostasis, Schattauer