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Radiolanthanides
Items for "Radiolanthanides"
A 140Nd/140Pr radionuclide generator based on physico-chemical transitions in 140Pr complexes after electron capture decay of 140Nd-DOTA
140Nd was produced by irradiations of CeO2 and Pr2O3 targets leading to natCe(3He,xn) 140Nd and 141Pr(p,2n) 140Nd nuclear reactions...
Keywords: Radionuclide generator, Radiolanthanides, Hot atom chemistry, Radiochemical separation, Positron emission tomography
06/2007 | Radiochimica Acta, Oldenbourg WissenschaftsverlagBiological evaluation of 153Sm and 166Ho complexes with tetraazamacrocycles containing methylcarboxylate and/or methylphosphonate pendant arms
153Sm and 166Ho complexes with two series of tetraazamacrocyclic ligands containing methylcarboxylate and/or methylphosphonate pendant arms were synthesized and their charge, lipophilicity, protein binding and in vitro and in vivo behaviour evaluated...
Keywords: Radiolanthanides, Tetraazamacrocycles, Phosphonates, Carboxylates, Biodistribution
06/2007 | Radiochimica Acta, Oldenbourg WissenschaftsverlagRadiochemical and biological behaviour of 153Sm and 166Ho complexes anchored by a novel bis(methylphosphonate) tetraazamacrocycle
The novel bis(methylphosphonate) 2,2′-[4,10-bis(phosphonomethyl)-1,4,7,10-tetraazacyclododecane-1,7-diyl] diacetic acid, trans-H6DO2A2P, has been synthesized and characterized by multinuclear NMR spectroscopy (1H, 13C and 31P)...
Keywords: Radiolanthanides, Mixed-tetraazamacrocycles, Radiopharmaceuticals, Biodistribution
06/2007 | Radiochimica Acta, Oldenbourg WissenschaftsverlagRadiolanthanides in endoradiotherapy: an overview
Endoradiotherapy (targeted radionuclide therapy) is a systemic approach, involving a radiolabeled targeting vector with a well characterized biochemical strategy to selectively deliver a cytotoxic level of radiation to a disease site on a cellular/molecular level...
Keywords: Radiolanthanides, Nuclear reaction, Labelling, Bifunctional chelator, Radiation Dosimetry
06/2007 | Radiochimica Acta, Oldenbourg Wissenschaftsverlag