Asef is a member of the Dbl-family of guanine nucleotide exchange factors (GEFs) with a proposed specificity for the small GTPase Rac1...
Keywords: APC, ASEF, Cdc42, exchange factor, GEF, GTPase, Rac, Rho
01/2007 | Biological Chemistry, Walter de GruyterThe Rho family of small GTPases plays a central role in intracellular signal transduction, particularly in reorganization of the actin cytoskeleton...
Keywords: GTPase, p115-RhoGEF, p190-RhoGAP, PDZ-RhoGEF, Rac, Rho, Tiam1
03/2006 | Biological Chemistry, Walter de Gruyter