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Items for "PTSM"

Preparation of [61Cu]pyruvaldehyde-bis (N4-methylthiosemicarbazone) complex as a possible PET radiopharmaceutical

Copper-61 (T1/2=3.33 h) produced via the natZn(p,x) 61Cu nuclear reaction using natural zinc target, was separated from the irradiated target material by a two-step method developed in our laboratory and was used for the preparation of [61Cu]-pyruvaldehyde- bis (N4-methylthiosemicarbazone) ([61Cu]-PTSM) using an in house-made PTSM ligand...

Keywords: Copper-61, PTSM, Radiopharmaceutical, Cyclotron, PET

02/2006 | Radiochimica Acta, Oldenbourg Wissenschaftsverlag
Development of [103Pd]-labeled-bis(N4-methylthiosemicarbazone) complexes as possible therapeutic agents

Due to interesting tumor seeking properties of bis
-thiosemicarbazones, two radio palladium- bis -thiosemicarbazone complexes, i.e. , [ 103Pd]-pyruvaldehyde- bis(N4-methylthiosemicarbazone) ([ 103Pd] PTSM) and [ 103Pd]- di-acetyl-bis (N4-methylthiosemicarbazone) ([ 103Pd]ATSM) were prepared according to the analogy of radio copper homologs...

Keywords: Palladium-103, Palladium(II) complexes, Radiolabeling, bis-thiosemicarbazono complexes, PTSM

12/2006 | Radiochimica Acta, Oldenbourg Wissenschaftsverlag