SearchPublisher and Institutes
You are here: Home :: Keyword index :: phy bis ray :: protein-DNA interaction - Proton Donor and Acceptor Molecules 
proteomics
Items for "proteomics"
Modeling and Designing a Proteomics Application on PROTEUS
OBJECTIVES: Biomedical applications, such as analysis and management of mass spectrometry proteomics experiments, involve heterogeneous platforms and knowledge, massive data sets, and complex algorithms...
Keywords: bioinformatics, Grid-based problem-solving environments, Ontology, proteomics, workflow
01/2005 | Methods of Information in Medicine, SchattauerSELDI-TOF plasma profiles distinguish individuals in a protein C-deficient family with thrombotic episodes occuring before age 40
We tested the hypothesis that differences in the low-molecular-weight (500-20,000 Da) proteomic profile of plasma may be detectable between members of a protein C-deficient family who have suffered thrombotic events before age 40 compared to family members without a history of venous thrombosis...
Keywords: Venous thrombosis, SELDI-TOF, Mass spectrometry, proteomics, protein C deficiency
12/2006 | Thrombosis and Haemostasis, SchattauerMapping molecular landscapes inside cells
Cryoelectron tomography opens a window into the inner space of cells. It combines the potential of three-dimensional imaging with a close-to-life preservation of biological samples...
Keywords: cell biology, Electron microscopy, pattern recognition, proteomics, structural biology
10/2004 | Biological Chemistry, Walter de GruyterRegulation of redox-sensitive exofacial protein thiols in CHO cells
Thiols affect a variety of cell functions, an effect known as redox regulation, largely attributed to modification of transcription factors and intracellular signaling mechanisms...
Keywords: cysteine, N-acetylcysteine, proteomics, Redox, surface thiols
10/2006 | Biological Chemistry, Walter de GruyterElectrophoretic separations of cerebrospinal fluid proteins in clinical investigations
The cerebrospinal fluid (CSF) is a key sample in the research for novel molecular biomarkers of neurodegenerative disorders...
Keywords: cerebrospinal fluid, 2-D electrophoresis, dementia, proteomics, matrix assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF-MS), neurodegeneration
04/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterOptimization and evaluation of surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) with reversed-phase protein arrays for protein profiling
Surface-enhanced laser desorption/ionization (SELDI) time-of-flight mass spectrometry with protein arrays has facilitated the discovery of disease-specific protein profiles in serum...
Keywords: high-throughput, plasma protein profiling, proteomics, serum protein profiling, surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI TOF-MS)
04/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterProtein profiling as a diagnostic tool in clinical chemistry: a review
Serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) appears to be an important diagnostic tool for a whole range of diseases...
Keywords: biomarker, decision tree, diagnostic value, ovarian cancer, post-analytical conditions, pre-analytical conditions, prostate cancer, protein profiling, proteomics, surface-enhanced laser desorption/ionization time-of-flight mass spectrometry
12/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterAutomation of biochip array technology for quality results
Background: Proteomics' requirement for simultaneous measurement of multiple markers is now possible with biochip array technology...
Keywords: automated biochip array, protein arrays, proteomics, Quality Control, standardisation
12/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterSELDI-TOF-MS proteomics of breast cancer
The detection, diagnosis, and management of breast cancer rely on an integrated approach using clinical history, physical examination, imaging, and histopathology...
Keywords: biomarkers, breast cancer, diagnostics, proteomics, surface enhanced laser desorption/ionization (SELDI)
12/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterPreanalytical and analytical variation of surface-enhanced laser desorption-ionization time-of-flight mass spectrometry of human serum
Keywords: Mass spectrometry, proteomics, surface-enhanced laser desorption-ionization time-of-flight(SELDI-TOF), serum protein peaks
10/2006 | Clinical Chemical Laboratory Medicine, Walter de GruyterResearch translation: a new frontier for clinical laboratories
Translational research and translational medicine (referred to hereafter as translational research) are interchangeable terms that underline the pressing need to translate into practical benefits for those affected by disease the extensive investments divested by the private and public sectors in biomedical research...
Keywords: biomarkers, clinical practice, Genomics, laboratory information, proteomics, scientific knowledge, translational research
11/2006 | Clinical Chemical Laboratory Medicine, Walter de GruyterHow to comprehensively analyse proteins and how this influences nutritional research
Proteomics, the comprehensive analysis of a protein complement in a cell, tissue or biological fluid at a given time, is a key platform within the “omic” technologies that also encompass genomics (gene analysis), transcriptomics (gene expression analysis) and metabolomics (metabolite profiling)...
Keywords: biomarker, health, Mass spectrometry, nutrition, proteomics
03/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterGlobal approach to perinatal medicine: functional genomics and proteomics
Functional genomics (transcriptomics and proteomics) is a global, systematic and comprehensive approach to the identification and description of the processes and pathways involved in normal and abnormal physiological states...
Keywords: biomarkers, DNA microarrays, functional genomics, Mass spectrometry, perinatal medicine, pre-eclampsia, preterm labor, proteomics, transcriptomics, two-dimensional electrophoresis
01/2005 | Journal of Perinatal Medicine, Walter de GruyterAnwendung der SELDI-TOF-Massenspektrometrie zur Identifizierung neuer Biomarker: Mglichkeiten und Grenzen / Application of SELDI-TOF-mass spectrometry for biomarker identification: potentials and limitations
Zusammenfassung Die SELDI-TOF-Massenspektrometrie (MS) ist eine der wichtigsten aktuell verfgbaren Technologien zur Hochdurchsatzanalyse von komplexen Proteinmischungen...
Keywords: Biomarkeridentifizierung, Massenspektrometrie, Proteinprofile, proteomics, SELDI-TOF-MS, biomarker identification, Mass spectrometry, protein profiling
06/2007 | LaboratoriumsMedizin, Walter de Gruyter