Items for "proteolysis / pericellular"

Plasminogen activator inhibitor-1 impairs plasminogen activation-mediated vascular smooth muscle cell apoptosis

The role of plasminogen activator inhibitor-1 (PAI-1) in vascular smooth muscle cell (VSMC) apoptosis mediated by plasminogen activation was studied with the use of aorticVSMC derived from mice with deficiency of PAI-1 (PAI-1 -/- ), tissue-type (t-PA -/- ) or urokinase-type (u-PA -/- ) plasminogen activator or from wildtype (WT) mice with corresponding genetic background...

Keywords: Apoptosis, proteolysis / pericellular, plasminogen activators, plasminogen activator inhibitors, plasminogen (-fragments)