The formation of active matrix metalloprotease-2 (MMP-2) requires the proteolytic processing of proMMP-2, a process that can occur through the formation of a ternary complex between proMMP-2, the tissue inhibitor of metalloprotease-2 and membrane type 1-MMP...
Keywords: chymase, mast cells, matrix metalloprotease, proteoglycan, serglycin
10/2006 | Biological Chemistry, Walter de Gruyter