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protein engineering
Items for "protein engineering"
A monomeric mutant of restriction endonuclease EcoRI nicks DNA without sequence specificity
We have mutated the monomer-monomer interface of the restriction endonuclease EcoRI in order to destabilize the homodimer and to stabilize heterodimers...
Keywords: heterodimer, nuclease, protein engineering, protein nucleic acid interaction, restriction enzyme, sequence specificity
10/2004 | Biological Chemistry, Walter de GruyterDocking of tryptophan analogs to trytophanyl-tRNA synthetase: implications for non-canonical amino acid incorporations
Non-canonical amino acids (NAA), as building blocks for peptides and proteins during ribosomal translation, represent a nearly infinite supply of novel functions...
Keywords: FlexX-Pharm, ligand docking, non-natural amino acids, protein engineering
09/2008 | Biological Chemistry, Walter de Gruyter