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Items for "protein degradation"

Structural properties of substrate proteins determine their proteolysis by the mitochondrial AAA+ protease Pim1

The protease Pim1/LON, a member of the AAA+ family of homo-oligomeric ATP-dependent proteases, is responsible for the degradation of soluble proteins in the mitochondrial matrix...

Keywords: mitochondria, Pim1 protease, protein degradation, substrate selectivity

12/2005 | Biological Chemistry, Walter de Gruyter
Regulation of proteasome-mediated protein degradation during oxidative stress and aging

Protein degradation is a physiological process required to maintain cellular functions...

Keywords: aging, oxidative stress, proteasome, protein degradation, protein oxidation

03/2008 | Biological Chemistry, Walter de Gruyter