The protease Pim1/LON, a member of the AAA+ family of homo-oligomeric ATP-dependent proteases, is responsible for the degradation of soluble proteins in the mitochondrial matrix...
Keywords: mitochondria, Pim1 protease, protein degradation, substrate selectivity
12/2005 | Biological Chemistry, Walter de GruyterProtein degradation is a physiological process required to maintain cellular functions...
Keywords: aging, oxidative stress, proteasome, protein degradation, protein oxidation
03/2008 | Biological Chemistry, Walter de Gruyter