Items for "protein-ligand interaction"

Comparative thermodynamic analysis of cyclic nucleotide binding to protein kinase A

We have investigated the thermodynamic parameters and binding of a regulatory subunit of cAMP-dependent protein kinase (PKA) to its natural low-molecular-weight ligand, cAMP, and analogues thereof...

Keywords: cAMP-dependent protein kinase, isothermal titration calorimetry, protein-ligand interaction, surface plasmon resonance