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Items for "protease-activated receptor"

Acute tissue-type plasminogen activator release in human microvascular endothelial cells: The roles of Gq, PLC-, IP3 and 5,6-epoxyeicosatrienoic acid

The acute physiologic release of tissue-type plasminogen activator (t-PA) from the endothelium is critical for vascular homeostasis...

Keywords: Tissue-type plasminogen activator, signal transduction, pharmacology, thrombin, protease-activated receptor, epoxyeicosatrienoic acids (EET’s)

00/0000 | Thrombosis and Haemostasis, Schattauer
Functional responses of bone cells to thrombin

Cells responsible for the formation and maintenance of bone express thrombin-responsive members of the protease-activated receptor family of G protein-coupled receptors...

Keywords: bone healing, intracellular calcium, osteoblast, osteoclast, phosphoinositol metabolism, prostaglandins, protease-activated receptor, thrombin

08/2006 | Biological Chemistry, Walter de Gruyter
Pathophysiology and diagnostic value of urinary trypsin inhibitors

Inflammation is an important indicator of tissue injury. In the acute form, there is usually accumulation of fluids and plasma components in the affected tissues...

Keywords: antiprotease, autoimmune disease, bikunin, C-reactive protein, chondroitin sulfate, elastase, infection, inflammation, inter-?-inhibitor, pro-enzyme, proteolytic enzyme, protease-activated receptor, serine protease, urinary trypsin inhibitor

01/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter