Items for "proprotein convertase"

The proprotein convertases and their implication in sterol and/or lipid metabolism

The proprotein convertases represent a family of nine proteinases, comprising seven basic amino acid-specific subtilisin-like serine proteinases related to yeast kexin, known as PC1/3, PC2, furin, PC4, PC5/6, PACE4 and PC7, and two other subtilases that cleave at non-basic residues, called SKI-1/S1P and NARC-1/PCSK9...

Keywords: cancer metastasis, cellular trafficking, cholesterol and lipid metabolism, proprotein convertase