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Items for "promoter"

Molecular structure and transcriptional regulation by nuclear factor-?B of the mouse kinin B₁ receptor gene

Kinins are important mediators in cardiovascular homeostasis, inflammation, and nociception...

Keywords: enhancer, lipopolysaccharide (LPS), mouse kinin B1 receptor gene, multiple transcription start sites, nuclear factor-?B (NF-?B), promoter, VSMC

06/2005 | Biological Chemistry, Walter de Gruyter

The K⁺ channel gene, Kcnb1: genomic structure and characterization of its 5?-regulatory region as part of an overlapping gene group

Kcnb1 expression is down-regulated in certain types of cardiomyopathy...

Keywords: ion channel, Kcnb1, overlapping gene group, promoter

09/2006 | Biological Chemistry, Walter de Gruyter

Increased carcinogenic potential of myeloid tumor cells induced by aberrant TGF-β1-signaling and upregulation of cathepsin B

The TGF-β signaling pathways are implicated in cancer. Cysteine cathepsins can contribute to the carcinogenic potential of tumor cells...

Keywords: Apoptosis, Cancer, cysteine, Migration, promoter, protease

06/2007 | Biological Chemistry, Walter de Gruyter

Identification and analysis of the promoter region of the type II transmembrane serine protease polyserase-1 and its transcript variants

Polyserase-1/TMPRSS9 and its alternative transcripts, serase-1B and serase-2B, are novel type II transmembrane serine proteases that may regulate physiological and pathological phenomena on the cell surface...

Keywords: E-box, gene regulation, polyserase-1, promoter, serase-1B, serase-2B, type II transmembrane serine proteases

01/2007 | Biological Chemistry, Walter de Gruyter

Association analysis of hepatitis virus B infection with haplotypes of the TBX21 gene promoter region in the Chinese population

Background: The T-box21 (TBX21) gene encodes the transcription factor T-bet (T-box expressed in T-cells), which influences naive T-lymphocyte development and has been implicated in the pathogenesis of many diseases.

Methods: We selected 208 hepatitis B patients and 213 healthy volunteers to examine whether polymorphisms or haplotypes of the TBX21 gene promoter were associated with hepatitis B virus (HBV) infection in the Chinese population...

Keywords: genetic susceptibility, haplotype, hepatitis B virus (HBV), promoter, TBX21 (T-box21) gene

03/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

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