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Items for "prion protein"

Cellular prion protein acquires resistance to proteolytic degradation following copper ion binding

The conversion of cellular prion protein (PrPC) into its pathological isoform (PrPSc) conveys an increase in hydrophobicity and induces a partial resistance to proteinase K (PK)...

Keywords: BSE, prion protein, proteinase K, proteolysis, scrapie

08/2004 | Biological Chemistry, Walter de Gruyter
Transgenic mouse brains for the evaluation and quality control of BSE tests

Rapid BSE tests are widely used diagnostics in veterinary medicine and more than 11 million tests are applied worldwide...

Keywords: bovine spongiform encephalopathy, prion protein, rapid BSE test, transgenic mouse

03/2007 | Biological Chemistry, Walter de Gruyter