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Items for "posttranslational modification"

First identification of a phosphorylcholine-substituted protein from Caenorhabditis elegans: isolation and characterization of the aspartyl protease ASP-6

Caenorhabditis elegans is a widely accepted model system for parasitic nematodes, drug screening and developmental studies...

Keywords: Mass spectrometry, nematodes, posttranslational modification, protease

10/2006 | Biological Chemistry, Walter de Gruyter
SUMOylation modulates transcriptional repression by TRPS1

Mutations or deletions of the TRPS1 gene on human chromosome 8q.24.1 cause the tricho-rhino-phalangeal syndromes (TRPS), which are characterized by craniofacial and skeletal malformations...

Keywords: GATA, posttranslational modification, repression domain, SUMO, TRPs, UBC9

04/2007 | Biological Chemistry, Walter de Gruyter
Glutaminyl cyclases from animals and plants: a case of functionally convergent protein evolution

Several mammalian peptide hormones and proteins from plant and animal origin contain an N-terminal pyroglutamic acid (pGlu) residue...

Keywords: posttranslational modification, protein maturation, pyroglutamic acid

08/2008 | Biological Chemistry, Walter de Gruyter