Protease nexin-1 (PN-1) is a non-circulating pericellular serpin expressed by vascular cells. PN-1 inhibits different proteases but when associated with glycosaminoglycans, its activity is mainly directed towards thrombin...
Keywords: Protease nexin-1, thrombin, smooth muscle cells, polysaccharides, fucoidans
00/0000 | Thrombosis and Haemostasis, Schattauer