Science.Online
Search
Publisher and Institutes
Akademie Verlag
Deutsches Institut für Urbanistik
Oldenbourg Wissenschaftsverlag
Walter de Gruyter
Schattauer
You are here: Home :: Keyword index :: par bis pre :: Polymorphic Transformations - ponderosa pine polymorphisms

Items for "polymorphisms"

A role for immunoglobulin G in donor-specific Streptococcus sanguis-induced platelet aggregation

There is increasing evidence for a relationship between bacterial infections and several cardiovascular disorders...

Keywords: Platelet, Fc ? RIIA, polymorphisms, IgG, Streptococcus sanguis

00/0000 | Thrombosis and Haemostasis, Schattauer
Identification of functional polymorphisms of the thromboxane A2 receptor gene in healthy volunteers

Thromboxane A2 receptor (TP) is an important actor in vascular physiology and plays a crucial role in the platelet activation process...

Keywords: genetics, Platelet, polymorphisms, thromboxane, TP

09/2006 | Thrombosis and Haemostasis, Schattauer
Lack of association between the 807 C/T polymorphism of glycoprotein Ia gene and post-treatment platelet reactivity after aspirin and clopidogrel in patients with acute coronary syndrome

Variability in platelet response to antiplatelet therapy and its clinical relevance have been well described...

Keywords: ADP receptors, polymorphisms, coronary syndrome, collagen receptors, antiplatelet agents

00/0000 | Thrombosis and Haemostasis, Schattauer
Associations of common polymorphisms in the thymidylate synthase, reduced folate carrier and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase genes with folate and homocysteine levels and venous thrombosis

Background: Folate is important in purine and thymidylate synthesis and, via homocysteine remethylation, facilitates S-adenosylmethionine-dependent transmethylation...

Keywords: folate, homocysteine, polymorphisms, recurrent venous thrombosis

04/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Polymorphisms in genes involved in DNA repair and metabolism of xenobiotics in individual susceptibility to sporadic diffuse gastric cancer

Background: Gastric cancer is the second highest cause of cancer mortality in the world, despite declining rates of incidence in many industrialized countries...

Keywords: diffuse gastric cancer, DNA repair, GSTM1, GSTP1, GSTT1, polymorphisms

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Inter-individual variation of inflammatory markers of cardiovascular risks and diseases

Cardiovascular diseases are a real public health problem and have multifactorial origin...

Keywords: atherosclerosis, environmental factors, intermediate phenotypes of inflammation, polymorphisms

07/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Comparison of the TaqMan and LightCycler systems in pharmacogenetic testing: evaluation of CYP2C9*2/*3 polymorphisms

Background: Pharmacogenetic testing for drug-metabolizing enzymes is not yet widely used in clinical practice.

Methods: In an attempt to facilitate the application of this procedure, we have compared two real-time PCR-based methods, the TaqMan® and the LightCycler? for the pharmacogenetic evaluation of CYP2C9*2/*3 polymorphisms.

Results and Conclusion: Both procedures are suitable for pharmacogenetic studies...

Keywords: cytochrome P450 (CYP450), pharmacogenetic testing, polymorphisms

03/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Association between polymorphisms of ACE, B2AR, ANP and ENOS and cardiovascular diseases: a community-based study in the Matsu area

Background: Cardiovascular diseases (CVDs) are the leading cause of death in most countries of the world...

Keywords: angiotensin-converting enzyme (ACE), atrial natriuretic peptide (ANP), ?2-adrenal receptor (B2AR), cardiovascular diseases, community-based, endothelial nitric oxide synthase (ENOS), polymorphisms

01/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Polymorphisms associated with apolipoprotein B levels in Greek patients with familial hypercholesterolemia

Background: Familial hypercholesterolemia (FH) is a genetic disorder characterized by high low-density lipoprotein-cholesterol (LDL-C) concentrations, which frequently gives rise to premature coronary artery disease...

Keywords: apolipoprotein B, familial hypercholesterolemia, fibrinogen, lipoprotein lipase, paroxonase, polymorphisms

07/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Lack of association between ?2B-adrenergic receptor polymorphism and risk of restenosis following coronary angioplasty and stent implantation – preliminary report

Background: A genetic association/prospective follow-up study was conducted to investigate whether genetic variation of the ?2B-adrenergic receptor gene was associated with the risk of restenosis in 96 Greek coronary artery disease patients undergoing coronary angioplasty and stent implantation.

Methods: For comparison of genotype frequency, a control group of 83 asymptomatic individuals was also studied...

Keywords: ?2B-adrenergic receptor, coronary heart disease, polymorphisms, restenosis

07/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Glutathione S-transferase variants increase susceptibility for late-onset Alzheimer's disease: association study and relationship with apolipoprotein E ?4 allele

Background: Several factors participate in the pathogenesis of Alzheimer's disease (AD), including free radicals, which when out of balance with their antioxidant capacity contribute to the oxidative stress process and neuronal death...

Keywords: apolipoprotein E, glutathione S-transferase, oxidative stress, polymorphisms

04/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Genetic profiling in healthy subjects from the Stanislas cohort based on 24 polymorphisms: effects on biological variables

Background: The association of genetic profiles with biological or clinical assessments is not clearly established especially among apparently healthy subjects.

Methods: A multivariate statistical analysis was performed on 24 polymorphisms related to the main metabolic pathways involved in cardiovascular diseases (CVDs)...

Keywords: cardiovascular diseases, Clusters, multivariate analysis, polymorphisms, predisposition

01/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
CD36 polymorphism and its relationship with body mass index and coronary artery disease in a Korean population

Background: CD36 is a multifunctional membrane receptor and a cell-adhesion molecule that is expressed in platelets, monocytes/macrophages, microvascular endothelial cells, cardiac monocytes and adipocytes...

Keywords: Body mass index, CD36, coronary artery disease, obesity, polymorphisms

10/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter