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Items for "platelet adhesion"

Pharmacologic inhibition of platelet vWF-GPIb interaction prevents coronary artery thrombosis

Under high shear arterial blood flow von Willebrand Factor (vWF) binds the platelet receptor glycoprotein (GP) Ib, leading to platelet adhesion, activation and thrombosis...

Keywords: Glycoprotein (GP) Iba, platelet adhesion, platelet agglutination, thrombosis, von Willebrand factor (vWF)

03/2006 | Thrombosis and Haemostasis, Schattauer
Soluble plasma-derived von Willebrand factor assembles to a haemostatically active filamentous network

The large glycoprotein von Willebrand factor (VWF) is involved in the initial haemostatic reaction mediating the interaction between platelets and the injured vessel wall...

Keywords: ULVWF multimers, platelet adhesion, atomic force microscopy, soluble VWF

04/2007 | Thrombosis and Haemostasis, Schattauer