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Items for "Plasmodium"

Plasmodium falciparum 2-Cys peroxiredoxin reacts with plasmoredoxin and peroxynitrite

Thioredoxin peroxidase 1 (TPx1) of the malarial parasite Plasmodium falciparum is a 2-Cys peroxiredoxin involved in the detoxification of reactive oxygen species and – as shown here – of reactive nitrogen species...

Keywords: antioxidant, malaria, peroxiredoxin, peroxynitrite, Plasmodium, plasmoredoxin, thioredoxin system

11/2005 | Biological Chemistry, Walter de Gruyter
Blocking effect of a biotinylated protease inhibitor on the egress of Plasmodium falciparum merozoites from infected red blood cells

The malaria parasite Plasmodium falciparum invades human red blood cells...

Keywords: affinity label, aziridine, cysteine protease inhibitor, malaria, Plasmodium

05/2005 | Biological Chemistry, Walter de Gruyter
Structural modifications to a high-activity binding peptide located within the PfEMP1 NTS domain induce protection against P. falciparum malaria in Aotus monkeys

Binding of P. falciparum-infected erythrocytes to vascular endothelium and to uninfected erythrocytes is mediated by the parasite-derived variant erythrocyte membrane protein PfEMP-1 and various receptors, both on the vascular endothelium and on the erythrocyte surface...

Keywords: binding, malaria, peptide, PfEMP-1, Plasmodium

01/2007 | Biological Chemistry, Walter de Gruyter