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plasminogen activators
Items for "plasminogen activators"
Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin v3 induces signal transduction and enhances plasminogen activation
It has been questioned whether there are receptors for urokinase-type plasminogen activator (uPA) that facilitate plasminogen activation other than the high affinity uPA receptor (uPAR/CD87) since studies of uPAR knockout mice did not support a major role of uPAR in plasminogen activation...
Keywords: Adhesion receptors / integrins, adhesion molecules, cell migration, Angiogenesis and inhibitors, plasminogen activators
03/2006 | Thrombosis and Haemostasis, SchattauerEndothelial dysfunction and systemic inflammation in persons with echolucent carotid plaques
Echolucent carotid plaques are associated with high risk for future ischemic cerebrovascular events independent of the degree of stenosis...
Keywords: atherosclerosis, ultrasound / diagnosis, von Willebrand factor, plasminogen activators, Cerebrovascular disease
07/2006 | Thrombosis and Haemostasis, SchattauerPlasminogen activator inhibitor-1 impairs plasminogen activation-mediated vascular smooth muscle cell apoptosis
The role of plasminogen activator inhibitor-1 (PAI-1) in vascular smooth muscle cell (VSMC) apoptosis mediated by plasminogen activation was studied with the use of aorticVSMC derived from mice with deficiency of PAI-1 (PAI-1 -/- ), tissue-type (t-PA -/- ) or urokinase-type (u-PA -/- ) plasminogen activator or from wildtype (WT) mice with corresponding genetic background...
Keywords: Apoptosis, proteolysis / pericellular, plasminogen activators, plasminogen activator inhibitors, plasminogen (-fragments)
11/2006 | Thrombosis and Haemostasis, Schattauer