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plasminogen activator inhibitors
Items for "plasminogen activator inhibitors"
Plasminogen activator inhibitor-1 impairs plasminogen activation-mediated vascular smooth muscle cell apoptosis
The role of plasminogen activator inhibitor-1 (PAI-1) in vascular smooth muscle cell (VSMC) apoptosis mediated by plasminogen activation was studied with the use of aorticVSMC derived from mice with deficiency of PAI-1 (PAI-1 -/- ), tissue-type (t-PA -/- ) or urokinase-type (u-PA -/- ) plasminogen activator or from wildtype (WT) mice with corresponding genetic background...
Keywords: Apoptosis, proteolysis / pericellular, plasminogen activators, plasminogen activator inhibitors, plasminogen (-fragments)
11/2006 | Thrombosis and Haemostasis, SchattaueruPAR uPA PAI-1 interactions and signaling: A vascular biologists view
The urokinase-type plasminogen activator (uPA), its inhibitor PAI-1 and its cellular receptor (uPAR), play a pivotal role in pericellular proteolysis...
Keywords: Urokinase / receptor, plasminogen activator inhibitors, Angiogenesis and inhibitors, atherosclerosis, restenosis
03/2007 | Thrombosis and Haemostasis, Schattauer