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Items for "plasminogen"

The gender-specific role of polymorphisms from the fibrinolytic, renin-angiotensin, and bradykinin systems in determining plasma t-PA and PAI-1 levels

Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) directly influence thrombus formation and degradation and thus risk for arterial thrombosis...

Keywords: epidemiological studies, thrombosis, risk factors, plasminogen, sex

10/2006 | Thrombosis and Haemostasis, Schattauer
Heparin modulation of human plasma kallikrein on different substrates and inhibitors

The interplay of different proteases and glycosaminoglycans is able to modulate the activity of the enzymes and to affect their structures...

Keywords: Antithrombin, C1-inhibitor, Factor XII, Glycosaminoglycans, plasminogen, synthetic substrates

08/2006 | Biological Chemistry, Walter de Gruyter
Plasminogen-dependent internalization of soluble melanotransferrin involves the low-density lipoprotein receptor-related protein and annexin II

We investigated the effect of plasminogen (Plg) on the internalization of recombinant soluble melanotransferrin (sMTf) using U87 human glioblastoma cells and murine embryonic fibroblasts (MEF) deficient in the low-density lipoprotein receptor-related protein (LRP)...

Keywords: annexin II, endocytosis, low-density lipoprotein receptor-related protein, plasminogen, soluble melanotransferrin

07/2007 | Biological Chemistry, Walter de Gruyter
Monitoring of fibrinolysis parameters during myocardial revascularization according to type of procedure

The aim of the study was to assess the effect of cardiothoracic surgery on the dynamics of plasminogen, D-dimers and plasminogen activator inhibitor (PAI-I) during the first 24 h after surgery...

Keywords: cardiopulmonary bypass, D-dimers, fibrinolysis, plasminogen activator inhibitor (PAI-I), plasminogen

01/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Cathepsin V, but not cathepsins L, B and K, may release angiostatin-like fragments from plasminogen

Cathepsin V is a lysosomal cysteine peptidase highly expressed in corneal epithelium; however, its function in the eye is still unknown...

Keywords: Angiogenesis, Angiostatin, corneal epithelium, cysteine cathepsins, plasminogen

02/2008 | Biological Chemistry, Walter de Gruyter