The plasma prekallikrein gene is expressed in many different human tissues at distinctly different levels and therefore tissue-specific control of the gene transcription is likely...
Keywords: alternative promoter, alternative transcription start site, Inr element, plasma kallikrein, plasma prekallikrein, promoter activity, TATA box, transcription start site, 5?-untranslated region heterogeneity
02/2005 | Biological Chemistry, Walter de GruyterPlasma prekallikrein (PPK) is synthesised in hepatocytes and secreted into the blood, where it participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation...
Keywords: cellular functions of plasma prekallikrein, kidney, KLKB1, pancreas, plasma kallikrein, plasma prekallikrein
09/2007 | Biological Chemistry, Walter de Gruyter