Adaptation of uteroplacental arteries in patients with early-onset preeclampsia combined with IUGR is compromized due to insufficient invasion of extravillous trophoblast cells (EVT) into the spiral artery wall...
Keywords: Endovascular trophoblast invasion, intrauterine growth restriction, leukemia inhibitory factor, macrophages, matrix-metalloproteases, periarterial trophoblast cells, placental bed, preeclampsia, uterine natural killer cells, uteroplacental arteries
08/2006 | Journal of Perinatal Medicine, Walter de GruyterThis article reviews the anatomy and physiology of the uterine circulation, with emphasis on the remodeling of spiral arteries during normal pregnancy, and the timing and anatomical pathways of trophoblast invasion of the spiral arteries...
Keywords: Atherosis, immunohistochemistry, impedance to blood flow, integrin, physiologic transformation of the spiral arteries, placental bed
12/2006 | Journal of Perinatal Medicine, Walter de Gruyter