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Items for "phosphoinositides"

Maximal Ca2+i stimulation of cardiac Na+/Ca2+ exchange requires simultaneous alkalinization and binding of PtdIns-4,5-P2 to the exchanger

Using bovine heart sarcolemma vesicles we studied the effects of protons and phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) on the affinity of the mammalian Na+/Ca2+ exchanger (NCX1) for intracellular Ca2+...

Keywords: Ca2+i regulatory site, Ca2+ transport, MgATP, Na+/Ca2+ countertransport, Na+i inhibition, pH, phosphoinositides

03/2007 | Biological Chemistry, Walter de Gruyter
Molecular biology of glutathione peroxidase 4: from genomic structure to developmental expression and neural function

Selenoproteins have been recognized as modulators of brain function and signaling...

Keywords: Apoptosis, embryogenesis, excitotoxicity, glial cells, oxidative stress, phosphoinositides, selenium

10/2007 | Biological Chemistry, Walter de Gruyter