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Items for "phosphatidylserine"

Flow cytometry-sorted non-viable endotoxin-treated human monocytes are strongly procoagulant

Monocytes/macrophages are important in disease states such as gram-negative sepsis and coronary artery disease...

Keywords: Tissue factor, Coagulation, phosphatidylserine, monocyte, sorting flow cytometry

07/2006 | Thrombosis and Haemostasis, Schattauer
Platelet microparticle membranes have 50- to 100-fold higher specific procoagulant activity than activated platelets

Platelet microparticles (PMPs) are small vesicles released from blood platelets upon activation. The procoagulant activity of PMPs has been previously mainly characterized by their ability to bind coagulation factors VIII and Va in reconstructed systems...

Keywords: Platelet, PMPs, procoagulant activity, spatial dynamics of coagulation, thrombin generation, factor X, phosphatidylserine, CD-61, CD-62P

03/2007 | Thrombosis and Haemostasis, Schattauer