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Items for "pharmacogenomics"

Impact of genetic polymorphisms on the risk of lipid disorders in patients on anti-HIV therapy

Active anti-HIV therapy can induce hypertriglyceridemia, low high-density lipoprotein (HDL) and insulin resistance, eventually accompanied by clinical lipodystrophy, associated loss of subcutaneous adipose tissue and an increase in abdominal adiposity...

Keywords: antiretroviral therapy, apolipoprotein A-V, apolipoprotein C-III, apolipoprotein E, dyslipidemia, HIV, lipodystrophy, pharmacogenomics, protease inhibitors, tumor necrosis factor-? (TNF?)

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Pharmacogenomics and adverse drug reactions in diagnostic and clinical practice

Pharmacogenetics and pharmacogenomics deal with genetically determined variations in how individuals respond to drugs...

Keywords: adverse drug reactions, CYP2D6, CYP2C9, CYP2C19, genetic polymorphism, pharmacogenetics, pharmacogenomics, therapeutic drug monitoring, thiopurine S-methyltransferase (TPMT), uridine diphosphate glucuronosyltransferase (UGT1A1)

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Pharmacogenomic genotyping methodologies

“Personalized medicine” based on an individual’s genetic makeup is slowly becoming a reality as pharmacogenomics moves from the research setting to the clinical laboratory...

Keywords: genotyping, pharmacogenomics, technologies

11/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Third Santorini conference pharmacogenomics workshop report: “Pharmacogenomics at the crossroads: what else than good science will be needed for the field to become part of Personalized Medicine?”

This workshop discussed the use of pharmacogenomics knowledge in clinical practice...

Keywords: education, industry, Personalized Medicine, pharmacogenomics, regulatory aspects

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter