Items for "persistent pulmonary hypertension of the newborn"

Inhaled nitric oxide therapy might reduce the need for hyperventilation therapy in infants with persistent pulmonary hypertension of the newborn

Aim: To determine whether inhaled nitric oxide might reduce the need for excessive respiratory alkalosis to maintain systemic oxygenation in infants with persistent pulmonary hypertension of the newborn (PPHN).

Materials and methods: A retrospective historical cohort study of 34 infants with PPHN with oxygenation index (OI) of 25 or more, including 19 infants without inhaled nitric oxide (i-NO) therapy (control group) and 15 infants with inhaled nitric oxide therapy (i-NO group) was performed...

Keywords: Hyperventilation, hypocapnia, inhaled nitric oxide therapy, meconium aspiration syndrome, normocapnia, oxygenation index, persistent pulmonary hypertension of the newborn