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Items for "peroxynitrite"

Plasmodium falciparum 2-Cys peroxiredoxin reacts with plasmoredoxin and peroxynitrite

Thioredoxin peroxidase 1 (TPx1) of the malarial parasite Plasmodium falciparum is a 2-Cys peroxiredoxin involved in the detoxification of reactive oxygen species and – as shown here – of reactive nitrogen species...

Keywords: antioxidant, malaria, peroxiredoxin, peroxynitrite, Plasmodium, plasmoredoxin, thioredoxin system

11/2005 | Biological Chemistry, Walter de Gruyter

N-Ethylmaleimide-sensitive factor: a redox sensor in exocytosis

Vascular injury triggers endothelial exocytosis of granules, releasing pro-inflammatory and pro-thrombotic mediators into the blood...

Keywords: endothelial cell, Hydrogen Peroxide, nitric oxide, peroxynitrite, Platelet, reactive oxygen species, superoxide, Weibel-Palade bodies

10/2006 | Biological Chemistry, Walter de Gruyter

Circulating levels of nitrated apolipoprotein A-I are increased in type 2 diabetic patients

Recent work has shown that high-density lipoprotein (HDL) isolated from human atherosclerotic lesions and the blood of patients with established coronary artery disease contains elevated levels of 3-nitrotyrosine and 3-chlorotyrosine...

Keywords: diabetes, high-density lipoprotein (HDL), macroangiopathy, myeloperoxidase, nitrosative stress, peroxynitrite

06/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Nitration of human plasminogen by RAW 264.7 macrophages reduces streptokinase-induced plasmin activity

Despite many years of study, clinical trials of new drugs to prevent thrombosis have often been disappointing...

Keywords: atherosclerosis, diabetes, fibrinolysis, nitrosative stress, peroxynitrite, phagocytes

02/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

A comparative study on the degradation of cotton linters induced by carbonate and hydroxyl radicals generated from peroxynitrite

Carbonate (CO₃^??) and hydroxyl (HO^?) radicals were chemically produced in cotton linter suspensions using peroxynitrite as a radical precursor...

Keywords: carbonate radical, cellulose, cotton linters, degradation, fibre, Hydroxyl radical, intramolecular selectivity, peroxynitrite

02/2005 | Holzforschung, Walter de Gruyter