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Items for "periodontal disease"

Roles of Arg- and Lys-gingipains in coaggregation of Porphyromonas gingivalis: identification of its responsible molecules in translation products of rgpA, kgp, and hagA genes

Arg- (Rgp) and Lys-gingipains (Kgp) are two individual cysteine proteinases produced by Porphyromonas gingivalis, an oral anaerobic bacterium, and are implicated as major virulence factors in a wide range of pathologies of adult periodontitis...

Keywords: Arg-gingipain, coaggregation, cysteine proteinase, Lys-gingipain, periodontal disease, Porphyromonas gingivalis

11/2004 | Biological Chemistry, Walter de Gruyter
The relationship between periodontal disease, bacterial vaginosis, and preterm birth

Spontaneous preterm labor leading to preterm birth is a major cause of perinatal mortality and morbidity worldwide...

Keywords: Bacterial vaginosis, clindamycin, Fusobacterium, hyperresponsive immune system, periodontal disease, periodontitis, preterm birth

04/2007 | Journal of Perinatal Medicine, Walter de Gruyter
Mechanism of methaemoglobin breakdown by the lysine-specific gingipain of the periodontal pathogen Porphyromonas gingivalis

The R- and K-gingipain proteases of Porphyromonas gingivalis are involved in proteolysis of haemoglobin from which the defensive dimeric haem pigment is formed...

Keywords: gingipains, haem, haemoglobin, periodontal disease, Porphyromonas, protease

09/2008 | Biological Chemistry, Walter de Gruyter