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Items for "peptide binding"

Tapasin and other chaperones: models of the MHC class I loading complex

MHC (major histocompatibility complex) class I molecules bind intracellular virus-derived peptides in the endoplasmic reticulum (ER) and present them at the cell surface to cytotoxic T lymphocytes...

Keywords: calreticulin, ERp57, major histocompatibility complex molecules, peptide binding, TAP, tapasin

09/2004 | Biological Chemistry, Walter de Gruyter
Nef protein of human immunodeficiency virus type 1 binds its own myristoylated N-terminus

HIV-1 Nef is a small protein (approx. 25 kDa) that is posttranslationally modified by myristoylation...

Keywords: fluorescence titration, peptide binding, protein conformation

02/2007 | Biological Chemistry, Walter de Gruyter