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Items for "peptide"

Unique neuronal functions of cathepsin L and cathepsin B in secretory vesicles: biosynthesis of peptides in neurotransmission and neurodegenerative disease

Proteases are required for the production of peptide neurotransmitters and toxic peptides in neurodegenerative diseases...

Keywords: ?-amyloid, cathepsin B, cathepsin L, enkephalin, neurodegenerative disease, neurology, peptide, peptide neurotransmission, secretory vesicles

10/2006 | Biological Chemistry, Walter de Gruyter
A sensitive proximity ligation assay for active PSA

Prostate-specific antigen (PSA) is a widely used marker for prostate cancer. The utility of PSA tests is limited by their inability to differentiate prostate cancer from non-malignant conditions such as benign prostatic hyperplasia and prostatitis...

Keywords: immunoassay, peptide, prostate cancer, prostate-specific antigen

06/2006 | Biological Chemistry, Walter de Gruyter
Structural modifications to a high-activity binding peptide located within the PfEMP1 NTS domain induce protection against P. falciparum malaria in Aotus monkeys

Binding of P. falciparum-infected erythrocytes to vascular endothelium and to uninfected erythrocytes is mediated by the parasite-derived variant erythrocyte membrane protein PfEMP-1 and various receptors, both on the vascular endothelium and on the erythrocyte surface...

Keywords: binding, malaria, peptide, PfEMP-1, Plasmodium

01/2007 | Biological Chemistry, Walter de Gruyter