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Items for "pancreas"

Role of the kinin B₁ receptor in insulin homeostasis and pancreatic islet function

Kinins are potent vasoactive peptides generated in blood and tissues by the kallikrein serine proteases...

Keywords: diabetes, glucose, insulin, kinin B1 receptor, kinins, pancreas

04/2006 | Biological Chemistry, Walter de Gruyter

Cellular expression of plasma prekallikrein in human tissues

Plasma prekallikrein (PPK) is synthesised in hepatocytes and secreted into the blood, where it participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation...

Keywords: cellular functions of plasma prekallikrein, kidney, KLKB1, pancreas, plasma kallikrein, plasma prekallikrein

09/2007 | Biological Chemistry, Walter de Gruyter

Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function

Tissue kallikrein (kallikrein 1) was first identified in pancreas and is the namesake of the kallikrein-related peptidase (KLK) family...

Keywords: kallikrein, mRNA splicing, pancreas, promoter analysis, tissue specific, Transcription factors

02/2008 | Biological Chemistry, Walter de Gruyter

Differential expression of ?-aminobutyric acid receptor A (GABA_A) and effects of homocysteine

Background: ?-Aminobutyric acid (GABA) is a known inhibitory neurotransmitter in the mammalian central nervous system, and homocysteine (Hcy) behaves as an antagonist for GABA_A receptor...

Keywords: brain, ?-aminobutyric acid receptor A (GABAA), heart, homocysteine, kidney, lung, mouse, muscimol, pancreas

12/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

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