Items for "oxidative damage"

Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids

Genomes and their precursor nucleotides are highly exposed to reactive oxygen species, which are generated both as byproducts of oxygen respiration or molecular executors in the host defense, and by environmental exposure to ionizing radiation and chemicals...

Keywords: 2-hydroxyadenine, 8-oxoguanine, MTH1, MUTYH, OGG1, oxidative damage