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Items for "oxaspirodion"

Inhibition of inducible TNF-? expression by oxaspirodion, a novel spiro-compound from the ascomycete Chaetomium subspirale

In a search for compounds inhibiting the inducible TNF-?a promoter activity in T cells, a new spiro-compound, designated oxaspirodion, was isolated from fermentations of the ascomycete Chaetomium subspirale...

Keywords: ERK, NF-?B, oxaspirodion, TNF-? synthesis

09/2004 | Biological Chemistry, Walter de Gruyter