Aims: c-erbB-2 overexpression has been shown to be a potential marker of aggressive biological behaviour in a varity of tumours, whereas its role played in thyroid papillary thyroid carcinoma (PTC) remains unclear...
Keywords: Papilläres Schilddrüsenkarzinom, c-erbB-2, Her-2/neu, Rezidiv, Onkogene
01/2005 | Nuklearmedizin, SchattauerDown-regulation of Ras signalling is mediated by specific GTPase-activating proteins (GAPs), which stimulate the very slow GTPase reaction of Ras by 105-fold...
Keywords: aluminium fluoride, beryllium fluoride, GTPase, GTPase-activating protein, neurofibromin, oncogene, Ras, transition state
09/2008 | Biological Chemistry, Walter de Gruyter