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Items for "oncogene"

Prognostic value of c-erbB-2 expression in papillary thyroid carcinoma

Aims: c-erbB-2 overexpression has been shown to be a potential marker of aggressive biological behaviour in a varity of tumours, whereas its role played in thyroid papillary thyroid carcinoma (PTC) remains unclear...

Keywords: Papilläres Schilddrüsenkarzinom, c-erbB-2, Her-2/neu, Rezidiv, Onkogene

01/2005 | Nuklearmedizin, Schattauer
Fluoride complexes of oncogenic Ras mutants to study the Ras-RasGAP interaction

Down-regulation of Ras signalling is mediated by specific GTPase-activating proteins (GAPs), which stimulate the very slow GTPase reaction of Ras by 105-fold...

Keywords: aluminium fluoride, beryllium fluoride, GTPase, GTPase-activating protein, neurofibromin, oncogene, Ras, transition state

09/2008 | Biological Chemistry, Walter de Gruyter