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Items for "nuclear receptor"

Ultraspiracle promotes the nuclear localization of ecdysteroid receptor in mammalian cells

The heterodimer consisting of ecdysteroid receptor (EcR) and ultraspiracle (USP), both of which are members of the nuclear receptor superfamily, is considered to be the functional ecdysteroid receptor...

Keywords: ecdysone, green fluorescent protein, nuclear receptor, subcellular distribution

05/2005 | Biological Chemistry, Walter de Gruyter
A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression

MDR1/P-glycoprotein is an efflux transporter determining the absorption and presystemic elimination of many xenobiotics in the gut...

Keywords: gene regulation, nuclear receptor, P-glycoprotein

06/2005 | Biological Chemistry, Walter de Gruyter
Specific inhibition of transcriptional activity of the constitutive androstane receptor (CAR) by the splicing factor SF3a3

The constitutive androstane receptor (CAR) is a member of the nuclear receptor superfamily and plays an important role in the degradation of xenobiotics in the liver...

Keywords: co-repressor, nuclear receptor, transcriptional regulation

10/2008 | Biological Chemistry, Walter de Gruyter