OBJECTIVE: Due to scarcity of calibration data for microarray experiments, simulation methods are employed to assess preprocessing procedures...
Keywords: Gene expression profiling, oligo-nucleotide array, normalization
01/2004 | Methods of Information in Medicine, SchattauerOBJECTIVES: The high density oligonucleotide microarrays from Affymetrix (Affymetrix GeneChips) are very popular in biomedical research...
Keywords: Affymetrix, microarray, normalization, data preprocessing
01/2005 | Methods of Information in Medicine, SchattauerOBJECTIVES: In two-channel microarray experiments the measured gene expression levels are affected by many sources of systematic variation...
Keywords: cDNA microarrays, two-color microarrays, normalization, loess regression, data preprocessing
01/2005 | Methods of Information in Medicine, SchattauerOBJECTIVES: A variety of linear models have recently been proposed for the design and analysis of microarray experiments...
Keywords: ANOVA techniques, hypothesis testing, normalization, experimental design
01/2005 | Methods of Information in Medicine, SchattauerKeywords: ?-glucuronidase, ?2-microglobulin, endogenous control, hypoxanthine phosphoribosyl transferase, normalization, quantitative reverse transcription PCR
11/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter