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nitric oxide
Items for "nitric oxide"
Role of the vascular wall in the pathophysiology of the acute coronary syndrome
The endothelium is of important significance in the development of the acute coronary syndrome. As an endo-/paracrine organ, the endothelium plays a key role in the regulation of the vascular homeostasis...
Keywords: Akutes Koronarsyndrom, Endotheldysfunktion, Stickstoffmonoxid, Atherosklerose
01/2006 | Hämostaseologie, SchattauerOxidative stress and endothelial dysfunction
This review focuses on the role of vascular oxidative stress in the development and progression of endothelial dysfunction...
Keywords: Endotheliale Dysfunktion, Lipoproteine, oxidativer Stress, Stickstoffmonoxid
01/2007 | Hämostaseologie, SchattauerCoagulation and endothelial dysfunction during longterm hyperdynamic porcine bacteremia effects of selective inducible nitric oxide synthase inhibition
Coagulation abnormalities have been implicated in the pathogenesis of sepsis and organ dysfunction. Nitric oxide (NO) is regarded as a critical mediator of many vascular pathologies, including sepsis...
Keywords: Coagulation, DIC, nitric oxide, oxidative stress, sepsis
00/0000 | Thrombosis and Haemostasis, SchattauerPrevention by NCX 4016, a nitric oxide-donating aspirin, but not by aspirin, of the acute endothelial dysfunction induced by exercise in patients with intermittent claudication
Ischemia/reperfusion damage evokes systemic inflammation and endothelial dysfunction in patients with intermittent claudication...
Keywords: Flow-mediated vasodilation, intermittent claudication, ischemia/ reperfusion injury, nitric oxide
03/2007 | Thrombosis and Haemostasis, SchattauerProtein disulphide isomerase-mediated LA419 NO release provides additional antithrombotic effects to the blockade of the ADP receptor
Despite the proven efficacy of current antithrombotic therapy in preventing ischemic heart disease (IHD), vascular events still occur...
Keywords: thrombosis, platelets, nitric oxide
04/2007 | Thrombosis and Haemostasis, SchattauerImpact of Mycoplasma hyorhinis infection on l -arginine metabolism: differential regulation of the human and murine iNOS gene
Infection with mycoplasma is a common problem in cell cultures, with
Keywords: inflammation, keratinocytes, NF-?B, nitric oxide
10/2005 | Biological Chemistry, Walter de GruyterPathogenetic interplay between osmotic and oxidative stress: the hepatic encephalopathy paradigm
Hepatic encephalopathy (HE) defines a primary gliopathy associated with acute and chronic liver disease...
Keywords: astrocytes, glutamate, glutamine synthetase, hepatic encephalopathy, liver, nitric oxide, NMDA receptor
10/2006 | Biological Chemistry, Walter de GruyterN -Ethylmaleimide-sensitive factor: a redox sensor in exocytosis
Vascular injury triggers endothelial exocytosis of granules, releasing pro-inflammatory and pro-thrombotic mediators into the blood...
Keywords: endothelial cell, Hydrogen Peroxide, nitric oxide, peroxynitrite, Platelet, reactive oxygen species, superoxide, Weibel-Palade bodies
10/2006 | Biological Chemistry, Walter de GruyterWhich endothelium-derived factors are really important in humans?
The endothelium plays a primary role in the local control of vascular function and structure, mainly by the production and release of NO, a potent vasodilator that also inhibits all the mechanisms involved in the pathogenesis of atherosclerosis, thus protecting the vessel wall against the development of atherosclerosis and thrombosis...
Keywords: circulation, endothelium, nitric oxide, oxidative stress, vascular reactivity
02/2006 | Biological Chemistry, Walter de GruyterAnti-inflammatory effects of kinins via microglia in the central nervous system
Kinins are important biologically active peptides that are up-regulated after lesions in both the peripheral and central (CNS) nervous systems...
Keywords: bradykinin, IL-1?, lipopolysaccharide, nitric oxide, prostaglandin E2, TNF-?
02/2006 | Biological Chemistry, Walter de GruyterCancer-preventive anti-oxidants that attenuate free radical generation by inflammatory cells
Active inflammatory leukocytes are a major endogenous source of reactive oxygen and nitrogen oxide species (RONS)...
Keywords: chemoprevention, co-culture, macrophage, mutagenesis, nitric oxide, phytochemicals, superoxide
04/2006 | Biological Chemistry, Walter de GruyterNitrite, a naturally occurring precursor of nitric oxide that acts like a ‘prodrug’
There are enzymatic and non-enzymatic mechanisms that generate NO? from nitrite in blood, stomach, saliva, urine and skin...
Keywords: nitrate, nitric oxide, nitrogen dioxide, skin, UVA
05/2006 | Biological Chemistry, Walter de GruyterNitric oxide modulates expression of extracellular matrix genes linked to fibrosis in kidney mesangial cells
Mesangial cells are thought to be important mediators of glomerular inflammation and fibrosis...
Keywords: connective tissue growth factor (CTGF), extracellular matrix, mesangial cells, nitric oxide, representational difference analysis (RDA), transcriptional regulation
05/2007 | Biological Chemistry, Walter de GruyterIntrauterine infection induced oligodendrocyte injury and inducible nitric oxide synthase expression in the developing rat brain
Keywords: 2, 3-cyclic nucleotide 3-phosphodiesterase, inducible nitric oxide synthase, intrauterine infection, nitric oxide, oligodendrocyte injury, white matter damage
06/2007 | Journal of Perinatal Medicine, Walter de GruyterNitric oxide covalently labels a 6-hydroxydopa-derived free radical intermediate in the catalytic cycle of copper/quinone-containing amine oxidase from lentil seedlings
The reaction of NO-derivatized polyamines called ‘NONOates’ with an amine oxidase from lentil seedlings was studied...
Keywords: cofactor, 6-hydroxydopa, Lens esculenta, lentil, nitric oxide
01/2005 | Biological Chemistry, Walter de GruyterImmune system-mediated endothelial damage is associated with NO and antioxidant system disorders
Two distinct systems of different origin are involved in the pathogenesis of both infectious and immunological vasculitis syndrome: nitric oxide (NO) from endothelial cells and granulocyte NADPH oxidase...
Keywords: catalase, endothelial damage, glutathione peroxidase, nitric oxide, nitric oxide synthase, superoxide dismutase
10/2004 | Clinical Chemical Laboratory Medicine, Walter de GruyterElevated levels of asymmetric dimethylarginine (ADMA) as a marker of cardiovascular disease and mortality
The endothelium plays a crucial role in the maintenance of vascular tone and structure by releasing the endothelium-derived vasoactive mediator, nitric oxide (NO)...
Keywords: coronary heart disease, endothelium, nitric oxide, Prognosis, risk factors
10/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterMeasurement of asymmetric dimethylarginine in plasma: methodological considerations and clinical relevance
Asymmetric dimethylarginine (ADMA) is a potent inhibitor of nitric oxide synthase and is regarded as a novel risk factor for cardiovascular disease...
Keywords: asymmetric dimethylarginine, cardiovascular disease, endothelial dysfunction, homocysteine, nitric oxide
10/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterAssessment of homocysteine, neopterin and nitric oxide levels in Behcet's disease
Keywords: homocysteine, immunity, neopterin, nitric oxide
01/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterEffects of nitric oxide and prostacyclin on hemodynamic response by big endothelin-1 in near term fetal sheep
Keywords: big endothelin-1, fetus, hypotension, 6-keto PGF1?), nitric oxide, sheep
11/2004 | Journal of Perinatal Medicine, Walter de GruyterAsymmetrisches Dimethylarginin (ADMA): ein neuer Marker zur Abschtzung des kardiovaskulren Risikos / Asymmetric dimethyl arginine (ADMA): a new marker for evaluating cardiovascular risk
Zusammenfassung Asymmetrisches Dimethylarginin (ADMA) ist eine endogen produzierte Aminosure, die alle drei Isoformen der Stickoxid-Synthase inhibiert...
Keywords: Asymmetrisches Dimethylarginin (ADMA), Atherosklerose, biomarker, endotheliale Dysfunktion, kardiovaskulres Risiko, Stickstoffmonoxid, atherosclerosis, aymmetric dimethyl arginine (ADMA), cardiovascular risk, coronary artery disease, endothelial dysfunction, nitric oxide
06/2007 | LaboratoriumsMedizin, Walter de GruyterNitric oxide and sphingolipids: mechanisms of interaction and role in cellular pathophysiology
Nitric oxide is a short-lived messenger with pleiotropic roles in the regulation of cell patho-physiological processes, including survival, death, proliferation and differentiation...
Keywords: Apoptosis, ceramide, cyclic GMP, inflammation, nitric oxide, sphingomyelinases, sphingosine-1-phosphate
11/2008 | Biological Chemistry, Walter de GruyterEffects of the Cdc2-like kinase-family and DNA topoisomerase I on the alternative splicing of eNOS in TNF-?-stimulated human endothelial cells
Nitric oxide (NO) is synthesized by endothelial nitric oxide synthase (eNOS) and plays an important role in vascular homeostasis and cardiovascular diseases...
Keywords: camptothecin, human umbilical vein endothelial cells (HUVECs), inflammation, nitric oxide, TG003
10/2008 | Biological Chemistry, Walter de GruyterEpigallocatechin gallate inhibits endothelial exocytosis
Consumption of green tea is associated with a decrease in cardiovascular mortality...
Keywords: flavonoid, granule, green tea, nitric oxide, vesicle trafficking, von Willebrand factor (vWF)
07/2008 | Biological Chemistry, Walter de GruyterSerum neopterin, nitric oxide, inducible nitric oxide synthase and tumor necrosis factor-? levels in patients with ischemic heart disease
Keywords: inducible nitric oxide synthase (iNOS), ischemic heart diseases, neopterin, nitric oxide, tumor necrosis factor-? (TNF-?)
08/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter