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Items for "nifedipine"

Feasibility of a randomized controlled trial testing nifedipine vs. placebo for the treatment of preterm labor

Aims: Nifedipine is believed to be a superior tocolytic agent on the basis of efficacy and side-effect profile, but was never prospectively evaluated in a placebo-controlled randomized clinical trial (RCT)...

Keywords: Feasibility study, nifedipine, preterm labor, randomized controlled trial, tocolysis

04/2007 | Journal of Perinatal Medicine, Walter de Gruyter
The quality of nifedipine studies used to assess tocolytic efficacy: a systematic review

Objective: To assess the quality of studies of nifedipine used to treat spontaneous preterm labor.

Design: A systematic review of study quality using a novel validity assessment tool, examining method-specific and topic-specific items in the domains of selection, performance and measurement biases.

Data Sources: Medline (1996–2003), EMBASE (1996–2003), BIOSIS (1993–2003), Current Contents (1995–2003), DERWENT DRUGFILE (1983–2003), Cochrane Database of Systematic Reviews...

Keywords: nifedipine, study quality, systematic reviews, tocolytics, tocolytic effectiveness, trial quality

07/2005 | Journal of Perinatal Medicine, Walter de Gruyter