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Items for "neutrophil"

Plasminogen activator inhibitor-1 potentiates LPS-induced neutrophil activation through a JNKmediated pathway

Plasminogen activator inhibitor-1 (PAI-1), a member of the serine protease inhibitor superfamily, modulates fibrinolysis by interacting with proteolytic mediators, including urokinase plasminogen activator (uPA)...

Keywords: PAI-1,Tnf-alpha, JNK kinase, neutrophil

05/2006 | Thrombosis and Haemostasis, Schattauer
Effects of elastase and cathepsin G on the levels of membrane and soluble TNF?

Neutrophil elastase (NE) and cathepsin G (CG), the proteolytic enzymes localized in azurophil granules of neutrophils (PMN), are involved in PMN responses to various stimuli...

Keywords: cathepsin G, elastase, inflammation, neutrophil, shedding, tumor necrosis factor ? (TNF?)

08/2005 | Biological Chemistry, Walter de Gruyter