Plasminogen activator inhibitor-1 (PAI-1), a member of the serine protease inhibitor superfamily, modulates fibrinolysis by interacting with proteolytic mediators, including urokinase plasminogen activator (uPA)...
Keywords: PAI-1,Tnf-alpha, JNK kinase, neutrophil
05/2006 | Thrombosis and Haemostasis, SchattauerNeutrophil elastase (NE) and cathepsin G (CG), the proteolytic enzymes localized in azurophil granules of neutrophils (PMN), are involved in PMN responses to various stimuli...
Keywords: cathepsin G, elastase, inflammation, neutrophil, shedding, tumor necrosis factor ? (TNF?)
08/2005 | Biological Chemistry, Walter de Gruyter