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Items for "neuroblastoma"

Characterisation of novel splicing variants of the tyrosine hydroxylase C-terminal domain in human neuroblastic tumours

Alternative splicing of human tyrosine hydroxylase (hTH) transcripts appears to occur mainly in the N-terminal domain, giving rise to at least eight different isoforms...

Keywords: adrenal medulla, alternative splicing, neuroblastoma, tyrosine hydroxylase isoforms

04/2007 | Biological Chemistry, Walter de Gruyter
The secretion of ibuprofen metabolites interferes with the capillary chromatography of urinary homovanillic acid and 4-hydroxy-3-methoxymandelic acid in neuroblastoma diagnosis

Neuroblastoma is the most common extracranial solid tumor in children. Abnormal secretion of catechol-amines in tissues and body fluids allows for the differential diagnosis of neuroblastoma from other neoplasms and its distinction from non-neoplastic inflammatory diseases...

Keywords: catabolites of catecholamine metabolism: homovanillic acid, 4-hydroxy-3-methoxymandelic acid (HVA, VMA), gas chromatography-mass-spectrometry (GC-MS), gas chromatography with flame ionization detection (GC-FID), homovanillic acid, 4-hydroxy-3-methoxymandelic acid, ibuprofen, neuroblastoma

04/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter