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Items for "natriuretic peptides"

Analytical and clinical performance of three natriuretic peptide tests in the emergency room

Background: The aim of the present study was to investigate the analytical and diagnostic utility of B-type natriuretic peptide (BNP) and the N-terminus of this prohormone, N-terminal pro-BNP (NT-pro-BNP) testing in the emergency department to identify acute congestive heart failure (CHF).

Methods: A blood sample taken from patients presenting to the emergency department with acute dyspnoea (n=80) was analyzed for natriuretic peptides using three different assays [Triage BNP (Biosite), Centaur BNP (Bayer) and Elecsys NT-pro-BNP (Roche)]...

Keywords: diagnosis, dyspnoea, Heart failure, natriuretic peptides, renal failure

05/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Long-term stability of endogenous B-type natriuretic peptide (BNP) and amino terminal proBNP (NT-proBNP) in frozen plasma samples

The aim of the present study was to assess the long-term stability of endogenous B-type natriuretic peptide (BNP) and amino terminal proBNP (NT-proBNP) in plasma samples stored at –20°C without addition of protease inhibitors (e.g., aprotinin)...

Keywords: Evaluation, Heart failure, natriuretic peptides, Plasma, stability

08/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Analytical evaluation of the Dade Behring Dimension RxL automated N-Terminal proBNP (NT-proBNP) method and comparison with the Roche Elecsys 2010

Methods to quantify B-type natriuretic peptide (BNP) and N-terminal-propeptide (NT-proBNP) in plasma or serum samples are well established...

Keywords: brain natriuretic peptide (BNP), Heart failure, natriuretic peptides, N-terminal proBNP (NT-proBNP)

11/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Multicentre evaluation of a new point-of-care test for the determination of NT-proBNP in whole blood

Background: The Roche CARDIAC proBNP point-of-care (POC) test is the first test intended for the quantitative determination of N-terminal pro-brain natriuretic peptide (NT-proBNP) in whole blood as an aid in the diagnosis of suspected congestive heart failure, in the monitoring of patients with compensated left-ventricular dysfunction and in the risk stratification of patients with acute coronary syndromes.

Methods: A multicentre evaluation was carried out to assess the analytical performance of the POC NT-proBNP test at seven different sites.

Results: The majority of all coefficients of variation (CVs) obtained for within-series imprecision using native blood samples was below 10% for both 52 samples measured ten times and for 674 samples measured in duplicate...

Keywords: analytical performance, brain natriuretic peptide (BNP), congestive heart failure, natriuretic peptides, N-terminal proBNP (NT-proBNP), point-of-care testing

10/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Ischemia-modified albumin and NT-prohormone-brain natriuretic peptide in peripheral arterial disease

Cardiovascular disease is the leading cause of mortality and morbidity in Western countries...

Keywords: Heart failure, ischemia-modified albumin, myocardial ischemia, natriuretic peptides, Peripheral arterial disease

02/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Clinical relevance of non-cardiac determinants of natriuretic peptide levels

There is evidence that natriuretic peptide (namely atrial and/or B-type natriuretic peptides) plasma concentration may be elevated in many clinical conditions besides cardiovascular diseases, the most frequent being lung diseases, renal and liver failure, acute cerebrovascular events, acute and chronic inflammatory diseases and certain metabolic and endocrine disorders...

Keywords: diagnostic accuracy, Heart failure, natriuretic peptides, renal failure

11/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Cardiovascular biomarkers: increasing impact of laboratory medicine in cardiology practice

The practice of cardiology is in continual evolution, in parallel with the progress achieved by medical research in understanding the pathophysiology of cardiovascular disease and in developing new therapeutic procedures...

Keywords: analytical performance, biomarkers, Cardiac troponin, cardiovascular disease, genomic analysis, natriuretic peptides

06/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

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