Endothelial NO synthase (eNOS) is the predominant enzyme responsible for vascular NO synthesis...
Keywords: l-arginine, asymmetric dimethyl-l-arginine, NADPH oxidase, oxidative stress, (6R)-5,6,7,8-tetrahydrobiopterin
12/2006 | Biological Chemistry, Walter de GruyterDespite substantial evidence indicating the association of hyperhomocysteinemia (hHcys) and end-stage renal disease (ESRD), the pathogenic role of increased plasma homocysteine (Hcys) levels in the progression of ESRD remains unclear...
Keywords: glomerular sclerosis, homocysteine, NADPH oxidase, Rac GTPase, superoxide
12/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter