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Items for "NADPH oxidase"

Janus-faced role of endothelial NO synthase in vascular disease: uncoupling of oxygen reduction from NO synthesis and its pharmacological reversal

Endothelial NO synthase (eNOS) is the predominant enzyme responsible for vascular NO synthesis...

Keywords: l-arginine, asymmetric dimethyl-l-arginine, NADPH oxidase, oxidative stress, (6R)-5,6,7,8-tetrahydrobiopterin

12/2006 | Biological Chemistry, Walter de Gruyter
Hyperhomocysteinemia – association with renal transsulfuration and redox signaling in rats

Despite substantial evidence indicating the association of hyperhomocysteinemia (hHcys) and end-stage renal disease (ESRD), the pathogenic role of increased plasma homocysteine (Hcys) levels in the progression of ESRD remains unclear...

Keywords: glomerular sclerosis, homocysteine, NADPH oxidase, Rac GTPase, superoxide

12/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter