Items for "myocardial infarction"

The role of platelets for the pathophysiology of acute coronary syndromes

Cardiovascular diseases, especially ischaemic heart disease, are actually the most frequent causes of death in the Western world and represent a central challenge for modern research and medicine...

Keywords: Akutes Koronarsyndrom, Atherosklerose, Thrombozyten, Myokardinfarkt

Acute coronary syndrome: peri-interventional antithrombotic therapy

In patients with acute coronary syndrome (ACS), the periinterventional antithrombotic treatment has become increasingly important for the choice of reperfusion strategy and as an adjunct pharmacological treatment prior, during and after percutaneous coronary interventions (PCI). In NSTE-ACS and early invasive strategy (<48 h), treatment with ASA, clopidogrel and heparin unfractionated heparin (UFH) preferred should be initiated as soon as possible...

Keywords: Akutes Koronarsyndrom, Myokardinfarkt, Antikoagulation, antithrombotische Therapie

C-reactive protein, interleukin-6 and tumor necrosis factor alpha as predictors of incident coronary and cardiovascular events and total mortality. A population-based, prospective study

Previous studies have shown an association between serum C-reactive protein (CRP) and cardiovascular disease (CVD) risk...

Keywords: cardiovascular disease, cytokines, inflammation, myocardial infarction

Rat models of myocardial infarction. Pathogenetic insights and clinical relevance

Animal models of cardiovascular pathology contribute towards understanding and treatment of a broad range of conditions...

Keywords: rat, Animal model, myocardial infarction, microvasculature

Potent arterial antithrombotic effect of direct factor-Xa inhibition with ZK-807834 administered to coronary artery disease patients

It was the objective of this study to evaluate the anti-thrombotic potency of direct factor-Xa inhibition with ZK-807834 in stable coronary patients, using an ex-vivo model of arterial thrombus formation...

Keywords: Coagulation, Coronary disease, myocardial infarction, thrombosis, platelets

Spatiotemporal correlation analyses: a new procedure for standardisation of DC magnetocardiograms

There is a lack of standard methods for the analysis of magnetocardiograms (MCGs)...

Keywords: Electrocardiography, magnetocardiography, myocardial infarction, repolarization, spatiotemporal analyses

High-sensitivity C-reactive protein concentration in patients with myocardial infarction-environmental factors, and polymorphisms in interleukin-10 and CD14 genes

Background: It has been shown that high-sensitivity C-reactive protein (hsCRP) concentrations are associated with elevated risk of myocardial infarction, but the mechanisms regulating hsCRP concentration are not completely elucidated yet...

Keywords: atherosclerosis, CD14, environmental factors, genetic polymorphisms, interleukin-10, myocardial infarction

TaqMan assays for genotyping of single nucleotide polymorphisms present at a disease susceptibility locus on chromosome 6

Multiple single-nucleotide polymorphisms in the BAT1-NFKBIL1-LTA region on the short arm of chromosome 6 have been found to be associated with susceptibility to myocardial infarction in a recent case-control study including individuals from Japan...

Keywords: haplotype, lymphotoxin-?, myocardial infarction, Polymorphism, TaqMan

Apolipoprotein A5 and triglyceridemia. Focus on the effects of the common variants

High plasma levels of triglycerides are an independent risk factor for the development of cardiovascular disease...

Keywords: apolipoprotein A5, myocardial infarction, Polymorphism, triglycerides

Cardiac natriuretic peptides after myocardial infarction: relationship with infarct size, left ventricular function and remodelling assessed by 99mTc-sestamibi gated-single photon emission tomography

Background: The aim of the study was to investigate the potential relationship between A-type (atrial) and B-type (brain) natriuretic peptides (ANP, BNP) and infarct size (IS), left ventricular (LV) function and remodelling as assessed by 99m technetium-hexakis-2-methoxy-isobutyl-isonitrile (99mTc-sestamibi) gated-single photon emission tomography (G-SPET).

Methods: Plasma concentrations of ANP and BNP in peripheral blood were measured in 54 patients with coronary artery disease (CAD) and previous myocardial infarction (MI)...

Keywords: atrial natriuretic peptide, brain natriuretic peptide, myocardial infarction, myocardial scintigraphy, ventricular remodelling