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Items for "mutation detection"

Rapid combined genotyping of factor V, prothrombin and methylenetetrahydrofolate reductase single nucleotide polymorphisms using minor groove binding DNA oligonucleotides (MGB probes) and real-time polymerase chain reaction

Risk factors for cardiovascular diseases and venous thromboembolism involve both acquired and hereditary conditions...

Keywords: minor groove binder, mutation detection, real-time polymerase chain reaction (PCR), single nucleotide polymorphism, thrombosis

12/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Improved real-time detection of the H63D and S65C mutations associated with hereditary hemochromatosis using a SimpleProbe assay format

Background: Genetic predisposition to hemochromatosis involves several different point mutations in the HFE gene...

Keywords: hemochromatosis, hybridization probes, LightCycler, mutation detection, SimpleProbe

07/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter