14-3-3 proteins affect the cell surface expression of several unrelated cargo membrane proteins, e.g., MHC II invariant chain, the two-pore potassium channels KCNK3 and KCNK9, and a number of different reporter proteins exposing Arg-based endoplasmic reticulum localization signals in mammalian and yeast cells...
Keywords: 14-3-3 proteins, Arg-based ER localization signal, cell surface trafficking, coatomer protein complex I (COPI), multimeric membrane proteins, peptide sorting motifs, Quality Control
09/2006 | Biological Chemistry, Walter de Gruyter