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Items for "mRNA splicing"

Kallikrein-related peptidase (KLK) family mRNA variants and protein isoforms in hormone-related cancers: do they have a function?

The kallikrein-related peptidase (KLK) gene family of 15 serine proteases encodes many proteins, including prostate specific antigen (PSA or KLK3), that are well described and/or are potential biomarkers for hormone-related cancers...

Keywords: mRNA splicing, nuclear localisation, serine protease, Transcriptome

06/2006 | Biological Chemistry, Walter de Gruyter
Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function

Tissue kallikrein (kallikrein 1) was first identified in pancreas and is the namesake of the kallikrein-related peptidase (KLK) family...

Keywords: kallikrein, mRNA splicing, pancreas, promoter analysis, tissue specific, Transcription factors

02/2008 | Biological Chemistry, Walter de Gruyter