Items for "misfolding"

Chemical chaperone-mediated protein folding: stabilization of P22 tailspike folding intermediates by glycerol

Polyol cosolvents like glycerol increase the thermal stability of proteins. This has been explained by preferential hydration favoring the more compact native over the denatured state...

Keywords: aggregation, bacteriophage P22, folding kinetics, misfolding, osmolyte, tailspike protein