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Items for "microRNA"

microRNA-guided posttranscriptional gene regulation

microRNAs (miRNAs) form an evolutionarily conserved and highly abundant class of non-coding RNAs that are 21–24 nucleotides (nt) in length...

Keywords: Argonaute proteins, double-stranded RNA, microRNA, posttranscriptional gene silencing, RNAi, translational regulation

12/2005 | Biological Chemistry, Walter de Gruyter

Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs

Fine-tuning of insulin secretion from pancreatic ?-cells participates in blood glucose homeostasis...

Keywords: exocytosis, insulin secretion, microRNA, neurotransmitter release, pancreatic ?-cell

03/2008 | Biological Chemistry, Walter de Gruyter

Kallikreins as microRNA targets: an in silico and experimental-based analysis

microRNAs (miRNAs) are non-coding RNAs that target specific mRNAs. They have been shown to control many biological processes including cancer pathogenesis...

Keywords: Cancer, kallikrein, KLK, microRNA, miRNA, RNAi, siRNA, tumor markers

06/2008 | Biological Chemistry, Walter de Gruyter

microRNAs: a new frontier in kallikrein research

microRNAs (miRNAs) are a recently discovered class of small non-coding RNAs that regulate gene expression...

Keywords: bioinformatics, kallikrein, KLK, microRNA, RNAi, target validation